Mu bioprocessing, kuchengetedza chaiko kutonga kwemamiriro ekunze kwakakosha.Chinonyanya kukosha pamamiriro aya ipH, iyo inopesvedzera kukura uye kubereka kwehutachiona kana maseru anoshandiswa mune akasiyana biotechnological application.Kuti uwane iyi chaiyo kudzora, bioreactor vanoshanda vanovimba nematurusi epamberi uye masensa-inonyanya kukosha kuve iyobioreactor pH sensor.
Bioreactor pH Sensor: Basic Principles yepH Measurement
1. Bioreactor pH Sensor: Tsanangudzo yepH
pH, kana kuti "inobvira yehydrogen," chiyero che acidity kana alkalinity yemhinduro.Inotara kuwanda kweiyo hydrogen ions (H+) mumhinduro yakapihwa uye inoratidzwa pachiyero chelogarithmic kubva pa0 kusvika pa14, ne7 inomiririra kusarerekera, hunhu huri pasi pe7 hunoratidza acidity, uye hutsika huri pamusoro pe7 hunoratidza alkalinity.Mu bioprocessing, kuchengetedza chaiyo pH nhanho kwakakosha pakukura kwakanyanya uye kubereka kwehutachiona kana maseru.
2. Bioreactor pH Sensor: pH Scale
Kunzwisisa chiyero chepH kwakakosha pakunzwisisa kukosha kwepH yekutarisa.Chimiro chelogarithmic chechiyero chinoreva kuti shanduko yeyuniti imwe inomiririra musiyano wakapetwa kagumi muhuwandu hwehydrogen ion.Uku kunzwa kunoita kuti kunyatso kudzora pH kuve kwakakosha mune bioreactors, uko kudiki kutsauka kunogona kukanganisa zvakanyanya bioprocess.
3. Bioreactor pH Sensor: Kukosha kwepH Monitoring muBioprocessing
Bioprocessing inosanganisira akasiyana mashandisirwo, anosanganisira kuvirisa, biopharmaceutical kugadzirwa, uye kurapwa kwemvura yetsvina.Mune imwe neimwe yeaya maitiro, kuchengetedza yakatarwa pH renji kwakakosha pakudzora maitiro enzymatic, kukura kwehutachiona, uye mhando yechigadzirwa.pH yekutarisa inova nechokwadi chekuti iyo bioreactor nharaunda inoramba iri mukati meinodiwa paramita, optimize chibereko uye goho rechigadzirwa.
4. Bioreactor pH Sensor: Zvinhu Zvinokanganisa pH muBioreactors
Zvinhu zvinoverengeka zvinogona kukanganisa pH mazinga mukati mebioreactors.Izvi zvinosanganisira kuwedzera kweasidhi kana alkaline zvinhu, metabolic byproducts yema microorganisms, uye shanduko yekushisa.Kutarisisa uye kudzora izvi zvinosiyana munguva chaiyo zvinogoneka nepH sensors, iyo inoita basa rakakosha mukutarisira bioprocess.
Bioreactor pH Sensor: Mhando dzepH Sensors
1. Bioreactor pH Sensor: Girazi Electrode pH Sensors
Girazi electrode pH sensors ndeimwe yemhando dzinonyanya kushandiswa mu bioprocessing.Izvo zvinosanganisira girazi membrane inopindura kune shanduko muhydrogen ion concentration.Aya masensa ane mukurumbira nekurongeka uye kuvimbika, zvichiita kuti ive sarudzo yakasarudzika yeakakosha bioreactor application.
2. Bioreactor pH Sensor: ISFET (Ion-Selective Field-Effect Transistor) pH Sensors
ISFET pH ma sensors akasimba-nyika midziyo inoona pH shanduko nekuyera voltage pasilicon chip.Ivo vanopa mabhenefiti akadai sekusimba uye kukodzera kwekamwe-kushandisa zvikumbiro, zvichiita kuti ive sarudzo inosiyana-siyana mu bioprocessing.
3. Bioreactor pH Sensor: Reference Electrodes
Reference electrodes chinhu chakakosha chepH sensors.Ivo vanopa yakagadzikana yereferensi mukana weiyo girazi electrode inoyera pH.Sarudzo yereferensi electrode inogona kukanganisa sensor performance, uye kusarudza musanganiswa wakakodzera kwakakosha pakuyera pH kuyerwa.
4. Bioreactor pH Sensor: Kuenzanisa kweSensor Types
Kusarudza iyo chaiyo pH sensor ye bioprocessing application zvinoenderana nezvinhu zvakaita sekurongeka, kusimba, uye kuenderana nezvinodiwa maitiro.Kuenzanisa kwemhando dzakasiyana dze sensor kuchabatsira bioprocess nyanzvi kuita sarudzo dzine ruzivo pakusarudza pH yekutarisa michina.
Bioreactor pH Sensor: Bioreactor pH Sensor Dhizaini
1. Bioreactor pH Sensor: Sensor Housing
Iyo sensor housing ndiyo yekunze shell iyo inodzivirira zvikamu zvemukati kubva munzvimbo yakaoma mukati me bioreactor.Pakusarudza zvinhu zvemba, zvakakosha kuti utarise zvinhu zvakaita sekuenderana kwemakemikari, kusimba, uye nyore kuchenesa.Simbi isina tsvina chinhu chinowanzo shandiswa nekuda kwekupokana kwayo nekuora uye kusimba.Chimiro uye saizi yeimba yacho inofanirwa kugadzirwa kuti ikwane izvo zvinodikanwa zvebioreactor uku uchive nechokwadi chekuisa uye kugadzirisa.
2. Bioreactor pH Sensor: Sensing Element
Mwoyo wepH sensor chinhu chayo chekunzwa.Bioreactor pH sensorskazhinji shandisa girazi electrode kana Ion-Sensitive Field Effect Transistor (ISFET) sechinhu chinonzwa.Magirazi emagetsi anozivikanwa nekurongeka uye kuvimbika kwawo, nepo ISFET ichipa zvakanakira maererano neminiaturization uye kusimba.Sarudzo pakati pezviviri izvi zvakanyanya zvinoenderana nezvinodiwa zvekushandisa.Kusarudza yakakodzera electrolyte mhinduro mukati mechinhu chekunzwa kwakakosha kuchengetedza kushanda kwe electrode nekufamba kwenguva.
3. Bioreactor pH Sensor: Reference Electrode
A referensi electrode yakakosha pakuyera pH sezvo ichipa yakagadzikana referensi poindi.Kune marudzi akasiyana-siyana ereferenzi electrode, anosanganisira Ag/AgCl uye Calomel electrodes.Maintenance kufunga kunosanganisira kuchengeta referensi electrode junction yakachena uye kuona kuti referensi mhinduro inoramba yakagadzikana.Kugara uchitarisa uye kuzadza mhinduro yekunongedza kunodiwa kuti uchengetedze huchokwadi.
4. Bioreactor pH Sensor: Junction Design
Iyo junction dhizaini yepH sensor yakakosha pakuchengetedza kuyerera kwemaion pakati peiyo process solution uye referensi electrode.Iyi dhizaini inofanirwa kudzivirira kuvhara uye kuderedza kudonha mukuverenga.Sarudzo yejunction zvinhu uye kumisikidzwa kwayo inoita basa rakakosha mukuita kwesensor kwese.
6. Bioreactor pH Sensor: Calibration Procedus
Calibration inhanho yakakosha mukuve nechokwadi cheiyo pH kuyerwa.pH sensors dzinofanirwa kuverengerwa nguva nenguva uchishandisa yakajairwa buffer mhinduro ine inozivikanwa pH kukosha.Maitiro ekugadzirisa anofanirwa kuteedzerwa zvine hungwaru, uye marekodhi ekugadzirisa anofanirwa kuchengetedzwa kuitira kuteedzera uye kudzora kunaka zvinangwa.
Bioreactor pH Sensor: Kuiswa uye Kubatanidzwa
1. Bioreactor pH Sensor: Kuiswa mukati meBioreactor
Kuiswa kwakaringana kwepH sensors mukati meiyo bioreactor kwakakosha kuti uwane zviyero zvinomiririra.Masensore anofanirwa kuve anowanikwa zvine hungwaru kuti atarise pH kusiyanisa mumudziyo wese.Iko kuisirwa kunofanirwawo kufunga nezvezvinhu zvakaita seyekutarisa sensor uye chinhambwe kubva kune agitator.
2. Bioreactor pH Sensor: Connection to Control Systems
Bioreactor pH sensors inofanirwa kubatanidzwa mune yekutonga system yeiyo bioreactor.Izvi zvinosanganisira kubatanidza sensor kune transmitter kana controller iyo inogona kududzira iyo pH kuverenga uye kugadzirisa zvinodiwa kuchengetedza iyo inodiwa pH level.
3. Bioreactor pH Sensor: Cable uye Connector Kufunga
Kusarudza tambo dzakakodzera uye zvibatanidza kwakakosha kune yakavimbika data kutapurirana uye hupenyu hurefu.Matambo anofanirwa kugadzirwa kuti akwanise kumira nemamiriro akaomarara mukati meiyo bioreactor, uye zvinobatanidza zvinofanirwa kusaita corrosion kuchengetedza kugadzikana kwemagetsi.
Bioreactor pH Sensor: Calibration uye Maintenance
1. Bioreactor pH Sensor: Calibration Procedus
Kugaro gadzirisa kwakakosha kuti uve nechokwadi cheiyo pH kuyerwa.Iyo frequency yecalibration inoenderana nezvinhu zvakaita sekugadzikana kwe sensor uye kukosha kwepH kutonga mukuita.Inokurudzirwa kutevera mazano emugadziri wekugadzirisa maitiro.
2. Bioreactor pH Sensor: Frequency of Calibration
Iyo frequency yecalibration inofanirwa kutariswa zvichibva pane chaiyo application uye kugadzikana kwe sensor.Mamwe masensa anogona kuda kudzokororwa kazhinji, nepo mamwe achigona kuchengetedza kurongeka kwenguva yakareba.
3. Bioreactor pH Sensor: Kuchenesa uye Kuchengetedza
Kuchenesa kwakakodzera uye kugadzirisa kwakakosha kune sensor hupenyu hurefu uye huchokwadi.Maitiro ekuchenesa anofanirwa kuitwa nguva nenguva kuti abvise chero biofilm kana madhipoziti anogona kuunganidza pane sensor pamusoro.Maintenance inofanirawo kusanganisira kutarisa referensi electrode uye junction yezviratidzo zvekupfeka kana kusvibiswa.
4. Bioreactor pH Sensor: Troubleshooting Common Issues
Kunyangwe dhizaini nekugadzirisa kwakaringana, pH sensors inogona kusangana nenyaya dzakadai sekudonha, ruzha rwechiratidzo, kana kushatisa electrode.Matanho ekugadzirisa matambudziko anofanirwa kunge aripo ekuona uye kugadzirisa nyaya idzi nekukasira kuderedza kuvhiringika kwemaitiro.
Mhedziso
Thebioreactor pH sensorchishandiso chakakosha mukugadzira bioprocessing, inobvumira kunyatso kudzora kwemazinga epH kukwirisa kukura kwehutachiona uye goho rechigadzirwa.Kunzwisisa misimboti yekuyera pH uye mhando dzakasiyana dzepH sensors dziripo kunopa simba vashandisi vebioprocess kuita sarudzo dzine ruzivo mukusarudza michina yakakodzera kwazvo yekushandisa kwavo.Iine akavimbika pH sensors kubva kune vanopa seShanghai BOQU Instrument Co., Ltd., bioprocessing nyanzvi dzinogona kuenderera mberi nekusimudzira munda webiotechnology uye kugadzira zvigadzirwa zvemhando yepamusoro.
Nguva yekutumira: Sep-13-2023
